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Anti-Caspase-14 Antibody-FITC (5W237)
还可以产品编号 TMAY-02109F
Anti-Caspase-14 Antibody-FITC (5W237) 是一种 FITC-conjugated Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody-FITC (5W237) 可用于 FCM。
Anti-Caspase-14 Antibody-FITC (5W237)
Anti-Caspase-14 Antibody-FITC (5W237)
还可以产品编号 TMAY-02109F
Anti-Caspase-14 Antibody-FITC (5W237) 是一种 FITC-conjugated Mouse 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody-FITC (5W237) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-Caspase-14 Antibody-FITC (5W237) is a FITC-conjugated Mouse antibody targeting Caspase-14. Anti-Caspase-14 Antibody-FITC (5W237) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 5W237 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CASP14 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with FITC Mouse anti-Human CASP14. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser2-Gln242) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human Caspase-14 / CASP14 protein (TMPY-01824) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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