Name: Iopamidol
Brand: TargetMol
SKU: T1576
Price: 164 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

25 mg

¥ 193

In stock

50 mg

¥ 289

In stock

100 mg

¥ 415

In stock

500 mg

¥ 1,120

In stock

1 mL x 10 mM (in DMSO)

¥ 164

In stock

产品介绍

生物活性

产品描述	Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.
体外活性	Iopamidol significantly decreases the rate of atrial contraction to a greater extent than either formulation of iodixanol. Iopamidol decreases papillary muscle force development more than the sodium formulation of iodixanol[3].
体内活性	Iopamidol increases systolic blood pressure (SBP), mean arterial pressure (MAP), and peak left ventricular pressure (LVP). Iopamidol increases LVP and LV end diastolic pressure to a greater extent than the cationic formulation of iodixanol. Thus iopamidol affects cardiovascular parameters more than iodixanol[3].
细胞实验	Chondrocytes are plated on 96 well plates at a density of 1 x 106 cells/cm2 . After overnight incubation in standard tissue culture conditions, contrast agents (including iopamidol) are introduced to wells in varying concentrations. Following 16 hour incubation with PBS and contrast agents, chondrocyte viability is assessed using the Live/Dead stain kit and quantified using the CellTiter-Glo Luminescent Cell Viability Assay. (Only for Reference)
别名	碘帕醇, SQ-13396, Niopam, Isovue, Iopamiron, Iopamiro, B-15000

化学信息

分子量	777.09
分子式	C₁₇H₂₂I₃N₃O₈
CAS No.	60166-93-0
Smiles	C(NC(CO)CO)(=O)C1=C(I)C(C(NC(CO)CO)=O)=C(I)C(NC([C@H](C)O)=O)=C1I
密度	2.281 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 92 mg/mL (118.39 mM), Sonication is recommended.

DMSO: 93 mg/mL (119.68 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (4.25 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2869 mL	6.4343 mL	12.8685 mL	64.3426 mL
5 mM	0.2574 mL	1.2869 mL	2.5737 mL	12.8685 mL
10 mM	0.1287 mL	0.6434 mL	1.2869 mL	6.4343 mL
20 mM	0.0643 mL	0.3217 mL	0.6434 mL	3.2171 mL
50 mM	0.0257 mL	0.1287 mL	0.2574 mL	1.2869 mL
100 mM	0.0129 mL	0.0643 mL	0.1287 mL	0.6434 mL

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments

一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent

DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH₂O，那么您的工作液浓度为 2 mg/mL 。

母液配置方法: 2 mg 药物溶于 50 μLDMSO TargetMol | reagent

（母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法: 取 50μLDMSO TargetMol | reagent

母液，添加 300 μLPEG300 TargetMol | reagent

混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH₂O TargetMol | reagent

混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300/ PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

Iopamidol

Iopamidol

产品介绍

计算器

体内实验配液计算器

剂量转换

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