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Anti-Selenoprotein W Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Selenoprotein W。Anti-Selenoprotein W Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Selenoprotein W Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Selenoprotein W。Anti-Selenoprotein W Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,165 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-Selenoprotein W Polyclonal Antibody is a Rabbit antibody targeting Selenoprotein W. Anti-Selenoprotein W Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
Ig Type | IgG |
交叉反应 | Rat (predicted:Human,Mouse,Sheep) |
验证活性 | Paraformaldehyde-fixed, paraffin embedded (Rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Selenoprotein W) Polyclonal Antibody, Unconjugated (TMAB-01672) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cytoplasm. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A pseudogene for this locus has been identified on chromosome 10. [provided by RefSeq, May 2017]. |
免疫原 | KLH conjugated synthetic peptide: mouse Selenoprotein W |
抗原种属 | Mouse |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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