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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Selenoprotein W Polyclonal Antibody

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货号 TMAB-01672

别名 SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482

Anti-Selenoprotein W Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Selenoprotein W。Anti-Selenoprotein W Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-Selenoprotein W Polyclonal Antibody

Anti-Selenoprotein W Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01672 别名 SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482

Anti-Selenoprotein W Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Selenoprotein W。Anti-Selenoprotein W Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Selenoprotein W Polyclonal Antibody is a Rabbit antibody targeting Selenoprotein W. Anti-Selenoprotein W Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名SEPW1, SELW_RAT, SELW, Selenoprotein W, MGC105482
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Sheep)
验证活性
Paraformaldehyde-fixed, paraffin embedded (Rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Selenoprotein W) Polyclonal Antibody, Unconjugated (TMAB-01672) at 1:500 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Ubiquitously expressed with highest levels in skeletal muscle and heart, moderate levels in brain, spinal cord, thyroid, spleen, prostate, ovary, small intestine and colon, and lowest levels in liver and lymph node.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is highly expressed in skeletal muscle and brain. It belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Studies in mouse show that this selenoprotein is involved in muscle growth and differentiation, and in the protection of neurons from oxidative stress during neuronal development. A pseudogene for this locus has been identified on chromosome 10. [provided by RefSeq, May 2017].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Selenoprotein W
抗原种属
Mouse
基因名称
SELENOW
蛋白名称
Selenoprotein W
功能
Plays a role as a glutathione (GSH)-dependent antioxidant. May be involved in a redox-related process. May play a role in the myopathies of selenium deficiency.
化学信息
分子量Theoretical: 9.5 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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