规格

价格

库存

数量

1 mg

¥ 398

现货

5 mg

¥ 877

现货

10 mg

¥ 1,570

现货

25 mg

¥ 2,660

现货

50 mg

¥ 3,890

现货

100 mg

¥ 5,550

现货

200 mg

¥ 7,550

现货

生物活性

产品描述	ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, a valine-conjugated prodrug of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound.
体内活性	ALZ-801与Tramiprosate在雄性CD-1小鼠的血浆和大脑中的比例分别为1.8和3.1[1]。经口给予ALZ-801（单剂量；172 mg/kg）后，在血浆和大脑中的平均AUCt值分别为58,758和5841 ng/ml.h。
别名	Valiltramiprosate

化学信息

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: < 1 mg/mL (insoluble)

H2O: 130 mg/mL (545.53 mM), Sonication is recommended.

溶液配制表

H2O