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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Complement component C9b Polyclonal Antibody

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货号 TMAB-04550

Anti-Complement component C9b Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Complement component C9b。Anti-Complement component C9b Polyclonal Antibody 可用于 WB,FCM。

Anti-Complement component C9b Polyclonal Antibody

Anti-Complement component C9b Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04550

Anti-Complement component C9b Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Complement component C9b。Anti-Complement component C9b Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Complement component C9b Polyclonal Antibody is a Rabbit antibody targeting Complement component C9b. Anti-Complement component C9b Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Sheep)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
组织特异性Plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Complementcomponent C9b
抗原种属
Human
基因名称
C9
基因ID
735
蛋白名称
Complement component C9
Uniprot ID
P02748
功能
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
化学信息
分子量Theoretical: 32/61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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