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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-CD243 Monoclonal Antibody (7B686)

Synonyms: PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20
货号 TMAT-0339 一键复制产品信息
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Anti-CD243 Monoclonal Antibody (7B686) 是一种 Mouse 抗体，靶向 CD243。Anti-CD243 Monoclonal Antibody (7B686) 可用于 FCM。

Anti-CD243 Monoclonal Antibody (7B686)

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货号 TMAT-0339

别名 PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20

Anti-CD243 Monoclonal Antibody (7B686) 是一种 Mouse 抗体，靶向 CD243。Anti-CD243 Monoclonal Antibody (7B686) 可用于 FCM。

Anti-CD243 Monoclonal Antibody (7B686)
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产品介绍

生物活性
产品描述
Anti-CD243 Monoclonal Antibody (7B686) is a Mouse antibody targeting CD243. Anti-CD243 Monoclonal Antibody (7B686) can be used in FCM.
别名
PGY1, P-GP, MDR1, GP170, CLCS, ABCB1, ABC20
Ig Type
IgG1
克隆号
7B686
反应种属
Human
应用FCM
推荐剂量
FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD243 (AA: 1149-1280) expressed in E. Coli.
抗原种属
Human
基因名称
ABCB1
基因ID
5243
蛋白名称
ATP-dependent translocase ABCB1
Uniprot ID
P08183
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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