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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NDFIP2 Polyclonal Antibody

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货号 TMAB-09295

Anti-NDFIP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NDFIP2。Anti-NDFIP2 Polyclonal Antibody 可用于 WB。

Anti-NDFIP2 Polyclonal Antibody

Anti-NDFIP2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09295

Anti-NDFIP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NDFIP2。Anti-NDFIP2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NDFIP2 Polyclonal Antibody is a Rabbit antibody targeting NDFIP2. Anti-NDFIP2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endosome membrane. Golgi apparatus membrane. Endosome > multivesicular body membrane.
组织特异性Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NDFIP2 is a 336 amino acid protein that localizes to the membrane of both the endosome and the golgi apparatus. Expressed in kidney, heart, brain, lung, liver, placenta and skeletal muscle, Ndfip2 interacts with NEDD4 and NEDD4-L and is thought to be involved in endocytosis and in the NFⅹB and MAPK signaling pathways. Additionally, Ndfip2 may function as an adaptor protein that may recruit NEDD4 ubiquitin-protein ligases to protein trafficking machinery in the golgi. Ndfip2 is activated by T cells and may be ubiquitinated by NEDD4 or NEDD4-L, an event that does not affect Ndfip2 function. The gene encoding Ndfip2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NDFIP2
抗原种属
Human
基因名称
NDFIP2
基因ID
54602
蛋白名称
NEDD4 family-interacting protein 2
功能
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. May modulate EGFR signaling.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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