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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody

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Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody
产品编号 TMAC-03298
别名 p-PIM1 (Y309), p-PIM1 (Tyr309), PIM1 (p-Y309), PIM1 (p-Tyr309)

Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PIM1 (Tyr309)。Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody 可用于 WB。

Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody

Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody
产品编号 TMAC-03298 别名 p-PIM1 (Y309), p-PIM1 (Tyr309), PIM1 (p-Y309), PIM1 (p-Tyr309)

Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PIM1 (Tyr309)。Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIM1 (Tyr309). Anti-Phospho-PIM1 (Tyr309) Polyclonal Antibody can be used in WB.
别名p-PIM1 (Y309), p-PIM1 (Tyr309), PIM1 (p-Y309), PIM1 (p-Tyr309)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HUVEC cells treated with PMA using Pim-1 (Phospho-Tyr309) Antibody TMAC-03298. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5, FOXO3). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly the strong synergism between these two oncogenes in tumorigenesis.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 309(H-R-Y(p)-H-G) derived from Human Pim-1
抗原种属
human
Uniprot ID
P11309
化学信息
分子量Actual: 45 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pPIM1 (Y309)pPIM1 (Tyr309)PIM1 (pY309)PIM1 (pTyr309)PIM1 (phospho-Y309)PIM1 (phospho-Tyr309)

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