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FBPase1 Protein, Human, Recombinant (His, E. coli)

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货号 TMPJ-00815

别名 Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

FBPase1 Protein, Human, Recombinant (His, E. coli)
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FBPase1 Protein, Human, Recombinant (His, E. coli)

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Rating icon 还可以
货号 TMPJ-00815 别名 Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

规格价格库存数量
5 μg
¥ 385
6-8日内发货
10 μg
¥ 620
6-8日内发货
20 μg
¥ 958
2-4周
50 μg
¥ 1,730
2-4周
100 μg
¥ 2,970
2-4周
200 μg
¥ 5,550
2-4周
500 μg
¥ 12,100
2-4周
1 mg
¥ 17,300
2-4周
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
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资源下载:
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产品介绍

生物活性
产品描述
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
种属
Human
表达系统
E. coli
标签C-6xHis
蛋白编号P09467
氨基酸序列Ala2-Gln338
蛋白构建Ala2-Gln338
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20% Glycerol, pH 8.0.
别名Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量38 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

FBP-1FBP 1
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