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顶部生物活性储存和溶解信息计算器

Anti-ADAM10 Antibody (4B559)

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产品编号 TMAC-00085

别名 RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10

Anti-ADAM10 Antibody (4B559) 是一种 Rabbit 抗体，靶向 ADAM10。Anti-ADAM10 Antibody (4B559) 可用于 IP,WB。

Anti-ADAM10 Antibody (4B559)

Anti-ADAM10 Antibody (4B559)

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Rating icon 还可以
产品编号 TMAC-00085 别名 RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10

Anti-ADAM10 Antibody (4B559) 是一种 Rabbit 抗体，靶向 ADAM10。Anti-ADAM10 Antibody (4B559) 可用于 IP,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAM10 Antibody (4B559) is a Rabbit antibody targeting ADAM10. Anti-ADAM10 Antibody (4B559) can be used in IP,WB.
别名RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10
Ig Type
IgG
克隆号
4B559
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of ADAM10 on different cells lysates using anti-ADAM10 antibody at 1/500 dilution. Positive control: Line 1: Jurkat, Line 2: Hela.
verifiedActivity
应用IPWB
推荐剂量
WB: 1:500-2000; IP: 1:10-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O14672
化学信息
分子量Theoretical: 84 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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