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Anti-ADAM10 Antibody (4B559) 是一种 Rabbit 抗体,靶向 ADAM10。Anti-ADAM10 Antibody (4B559) 可用于 WB,IP。
Anti-ADAM10 Antibody (4B559) 是一种 Rabbit 抗体,靶向 ADAM10。Anti-ADAM10 Antibody (4B559) 可用于 WB,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-ADAM10 Antibody (4B559) is a Rabbit antibody targeting ADAM10. Anti-ADAM10 Antibody (4B559) can be used in WB,IP. |
别名 | RAK, Mammalian disintegrin metalloprotease, MADM, Kuzbanian protein homolog, Kuzbanian, Kuz, HsT18717, HsT 18717, Drosophila, CDw156, CD156c antigen, CD156c, CD 156c, ADAM metallopeptidase domain 10, ADAM 10, AD18, AD10, AD 10, A disintegrin and metalloproteinase domain 10, A disintegrin and metalloprotease domain 10 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of ADAM10 on different cells lysates using anti-ADAM10 antibody at 1/500 dilution. Positive control: Line 1: Jurkat, Line 2: Hela. |
应用 | |
推荐剂量 | WB: 1:500-2000; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFα (tumor necrosis factor α), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 84 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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