- 全部删除
- 您的购物车当前为空
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cortactin (Tyr466)。Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody 可用于 WB。
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-Cortactin (Tyr466)。Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,235 | 5日内发货 |
产品描述 | Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB. |
别名 | p-Cortactin (Y466), p-Cortactin (Tyr466), Cortactin (p-Y466), Cortactin (p-Tyr466) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from Jurkat cells untreated or treated with H2O2 using Cortactin (Phospho-Tyr466) Antibody TMAC-00942. 2. Western blot analysis of extracts from JK cells, treated with H2O2 or calf intestinal phosphatase (CIP), using Cortactin (Phospho-Tyr466) Antibody TMAC-00942. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 466 (P-V-Y(p)-E-T) derived from Human CORTACTIN |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容