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Anti-CD83 Antibody (4E53) 是一种 Rabbit 抗体,靶向 CD83。Anti-CD83 Antibody (4E53) 可用于 FCM。
Anti-CD83 Antibody (4E53) 是一种 Rabbit 抗体,靶向 CD83。Anti-CD83 Antibody (4E53) 可用于 FCM。
产品描述 | Anti-CD83 Antibody (4E53) is a Rabbit antibody targeting CD83. Anti-CD83 Antibody (4E53) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4E53 |
交叉反应 | Mouse |
验证活性 | Flow cytometric analysis of Mouse CD83 expression on LPS-stimulated BABL/c splenocytes. Cells were stained with purified anti-Mouse CD83, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD83 (rM CD83; TMPY-02156; O88324; Met1-Arg133). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD83 is considered as a marker of mature dendritic cells as well as an adhesion receptor that binds to resting monocytes and a subset of activated CD8+T cells. In certain conditions, CD83 tended to dimerize or even multimerize through its aberrant intermolecular disulfide bonds. The injection of CD83-Ig can significantly enhance the rate of tumor growth and inhibit the T cell growth. |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Mouse CD83 Protein (TMPY-02156) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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