购物车
- 全部删除
- 您的购物车当前为空
Anti-CLEC-2 Antibody (2F242) 是一种 Rabbit 抗体,靶向 CLEC-2。Anti-CLEC-2 Antibody (2F242) 可用于 ELISA。
Anti-CLEC-2 Antibody (2F242) 是一种 Rabbit 抗体,靶向 CLEC-2。Anti-CLEC-2 Antibody (2F242) 可用于 ELISA。
产品描述 | Anti-CLEC-2 Antibody (2F242) is a Rabbit antibody targeting CLEC-2. Anti-CLEC-2 Antibody (2F242) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2F242 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CLEC1B / CLEC2 (rh CLEC1B / CLEC2; TMPY-02357; Gln 58-Pro 229; NP_057593.3). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. CLEC2 contains 1 C-type lectin domain and is expressed preferentially in the liver. It acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CLEC1B / CLEC2 Protein (TMPY-02357) |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容