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Anti-CLEC-2 Antibody (2F242)

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Anti-CLEC-2 Antibody (2F242)
产品编号 TMAY-01394
别名 QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik

Anti-CLEC-2 Antibody (2F242) 是一种 Rabbit 抗体,靶向 CLEC-2。Anti-CLEC-2 Antibody (2F242) 可用于 ELISA。

Anti-CLEC-2 Antibody (2F242)
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Anti-CLEC-2 Antibody (2F242)

Rating icon 还可以
Anti-CLEC-2 Antibody (2F242)
产品编号 TMAY-01394 别名 QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik

Anti-CLEC-2 Antibody (2F242) 是一种 Rabbit 抗体,靶向 CLEC-2。Anti-CLEC-2 Antibody (2F242) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-CLEC-2 Antibody (2F242) is a Rabbit antibody targeting CLEC-2. Anti-CLEC-2 Antibody (2F242) can be used in ELISA.
别名QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik
Ig Type
Rabbit IgG
克隆号
2F242
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CLEC1B / CLEC2 (rh CLEC1B / CLEC2; TMPY-02357; Gln 58-Pro 229; NP_057593.3).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. CLEC2 contains 1 C-type lectin domain and is expressed preferentially in the liver. It acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CLEC1B / CLEC2 Protein (TMPY-02357)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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