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顶部生物活性储存和溶解信息计算器

Anti-IL-27RA/TCCR Polyclonal Antibody

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产品编号 TMAB-00958
别名 ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1

Anti-IL-27RA/TCCR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-27RA/TCCR。Anti-IL-27RA/TCCR Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-IL-27RA/TCCR Polyclonal Antibody

Anti-IL-27RA/TCCR Polyclonal Antibody

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产品编号 TMAB-00958 别名 ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1

Anti-IL-27RA/TCCR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IL-27RA/TCCR。Anti-IL-27RA/TCCR Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-27RA/TCCR Polyclonal Antibody is a Rabbit antibody targeting IL-27RA/TCCR. Anti-IL-27RA/TCCR Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat)
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
组织特异性Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, s
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Upon antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-b that augment the cell-mediated immune response, while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominantly expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IL27RA
抗原种属
Human
基因名称
IL27RA
基因ID
9466
蛋白名称
Interleukin-27 receptor subunit alpha
Uniprot ID
Q6UWB1
研究领域
STATs,Interleukins,STATs
功能
Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
化学信息
分子量Theoretical: 70 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

WSX 1CRL-1CRL 1

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