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Anti-CD5L Polyclonal Antibody

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货号 TMAB-00376

别名 SP-α, Spα, SP-ALPHA, Spalpha, PRO229, CD5 molecule-like, API6, AIM

Anti-CD5L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD5L。Anti-CD5L Polyclonal Antibody 可用于 IF, IHC-Fr, IHC-P。

Anti-CD5L Polyclonal Antibody

Anti-CD5L Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00376 别名 SP-α, Spα, SP-ALPHA, Spalpha, PRO229, CD5 molecule-like, API6, AIM

Anti-CD5L Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD5L。Anti-CD5L Polyclonal Antibody 可用于 IF, IHC-Fr, IHC-P。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD5L Polyclonal Antibody is a Rabbit antibody targeting CD5L. Anti-CD5L Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P.
别名SP-α, Spα, SP-ALPHA, Spalpha, PRO229, CD5 molecule-like, API6, AIM
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
验证活性
1. Tissue/cell: mouse lymphoma tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-CD5L/Api6 Polyclonal Antibody, Unconjugated (TMAB-00376) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Paraformaldehyde-fixed, paraffin embedded (rat spleen tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CD5L) Polyclonal Antibody, Unconjugated (TMAB-00376) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining.
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD5L
抗原种属
Human
基因名称
CD5L
基因ID
922
蛋白名称
CD5 antigen-like
Uniprot ID
O43866
研究领域
Survivin / IAPs
功能
May play a role in the regulation of the immune system. Seems to play a role as an inhibitor of apoptosis.
化学信息
分子量Theoretical: 36 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器

关键词

PRO-229PRO 229API-6API 6
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