购物车
- 全部删除
您的购物车当前为空
Anti-CRABP2 Antibody (8O852)
还可以产品编号 TMAY-03344
Anti-CRABP2 Antibody (8O852) 是一种 Rabbit 抗体，靶向 CRABP2。Anti-CRABP2 Antibody (8O852) 可用于 ELISA。
Anti-CRABP2 Antibody (8O852)
Anti-CRABP2 Antibody (8O852)
还可以产品编号 TMAY-03344
Anti-CRABP2 Antibody (8O852) 是一种 Rabbit 抗体，靶向 CRABP2。Anti-CRABP2 Antibody (8O852) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CRABP2 Antibody (8O852) is a Rabbit antibody targeting CRABP2. Anti-CRABP2 Antibody (8O852) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8O852 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CRABP2 (rM CRABP2; TMPY-02189; P22935; Pro 2-Glu 138). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cellular retinoic acid-binding protein 2, also known as Cellular retinoic acid-binding protein II, CRABP-II and CRABP2, is a protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The predicted amino acid sequences of human CRABP1 and CRABP2 demonstrated a 99.3% and 93.5% identity to mouse CRABP1 and CRABP2, respectively. CRABP2 forms a beta-barrel structure that accommodates hydrophobic ligands in its interior. Expression of CRABP2, but not CRABP1 mRNA, was markedly increased (greater than 15-fold) by retinoic acid treatment of fibroblasts cultured from human skin, whereas no significant induction of CRABP2 mRNA was observed in human lung fibroblasts. CRABP2 transports retinoic acid to the nucleus. It regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is necessary for elastin induction by All-trans retinoic acid (ATRA) in MRC-5 cells. It is expressed at low levels in emphysema fibroblasts. This alteration in the retinoic acid signalling pathway in lung fibroblasts may contribute to the defect of alveolar repair in human pulmonary emphysema. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse CRABP2 protein (TMPY-02189) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-CRABP2 Antibody (8O852) | purchase Anti-CRABP2 Antibody (8O852) | Anti-CRABP2 Antibody (8O852) cost | order Anti-CRABP2 Antibody (8O852)
嗨！有任何问题？点我咨询
评论内容