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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody

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货号 TMAB-10597

Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Dishevelled 2 (Ser143)。Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody

Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10597

Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Dishevelled 2 (Ser143)。Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Dishevelled 2 (Ser143). Anti-Phospho-Dishevelled 2 (Ser143) Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Danio rerio)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasmic vesicle. Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human Dishevelled 2 around the phosphorylation site of Ser143
抗原种属
Human
基因名称
DVL2
基因ID
1856
蛋白名称
Segment polarity protein dishevelled homolog DVL-2
Uniprot ID
O14641
功能
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes.
化学信息
分子量Theoretical: 81 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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