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Anti-human CD18 Antibody (9C890) 是一种 Mouse 抗体,靶向 human CD18。Anti-human CD18 Antibody (9C890) 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-human CD18 Antibody (9C890) 是一种 Mouse 抗体,靶向 human CD18。Anti-human CD18 Antibody (9C890) 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μg | ¥ 1,875 | 5日内发货 |
| 产品描述 | Anti-human CD18 Antibody (9C890) is a Mouse antibody targeting human CD18. Anti-human CD18 Antibody (9C890) can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | Mouse IgG1, k |
| 克隆号 | 9C890 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4). |
| 浓度 | 1mg/ml |
| 研究背景 | The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human CD18 |
| 抗原种属 | Human |
| 基因名称 | ITGB2 |
| 基因ID | |
| 蛋白名称 | Integrin beta-2 |
| Uniprot ID | |
| 功能 | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. |
| 分子量 | Theoretical: 82 kDa. Actual: 90-95 kDa. |
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |