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Anti-NF-kB p65 Antibody (9K999)

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货号 TMAC-02822

别名 v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3

Anti-NF-kB p65 Antibody (9K999) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9K999) 可用于 IHC,WB。

Anti-NF-kB p65 Antibody (9K999)

Anti-NF-kB p65 Antibody (9K999)

一键复制产品信息
Rating icon 还可以
货号 TMAC-02822 别名 v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3

Anti-NF-kB p65 Antibody (9K999) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9K999) 可用于 IHC,WB。

规格价格库存数量
50 μL
¥ 1,330
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍


生物活性
产品描述
Anti-NF-kB p65 Antibody (9K999) is a Mouse antibody targeting NF-kB p65. Anti-NF-kB p65 Antibody (9K999) can be used in IHC,WB.
别名v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3
克隆号
9K999
反应种属
Human,Mouse,Rat
验证活性
1. Western blot analysis of Hela (lane 1), 293T(lane 2) and HepG (lane 3), using TMAC-02822 diluted at 1:2,000.
2. Western blot analysis of Mouse Heart (lane 1), Rat Heart (lane 2), Rat Liver (lane 3) and Rat Spleen (lane 4), using TMAC-02822 diluted at 1:3,000.
3. IHC staining of mouse hippocampus tissue with NFκB p65 mouse mAb diluted at 1:200.
verifiedActivityverifiedActivityverifiedActivity
应用IHCWB
推荐剂量
WB: 1:1000-3000; IHC: 1:200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Affinity purification using immunogen.
性状Liquid
缓冲液Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection.
偶联与修饰
偶联
Unconjugated
抗原信息
Uniprot ID
化学信息
分子量Actual: 65 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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