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别名 v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3
Anti-NF-kB p65 Antibody (9K999) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9K999) 可用于 IHC,WB。
Anti-NF-kB p65 Antibody (9K999) 是一种 Mouse 抗体,靶向 NF-kB p65。Anti-NF-kB p65 Antibody (9K999) 可用于 IHC,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,330 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-NF-kB p65 Antibody (9K999) is a Mouse antibody targeting NF-kB p65. Anti-NF-kB p65 Antibody (9K999) can be used in IHC,WB. |
| 别名 | v-rel avian reticuloendotheliosis viral oncogene homolog A, p65, NFKB3 |
| 克隆号 | 9K999 |
| 反应种属 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Hela (lane 1), 293T(lane 2) and HepG (lane 3), using TMAC-02822 diluted at 1:2,000. 2. Western blot analysis of Mouse Heart (lane 1), Rat Heart (lane 2), Rat Liver (lane 3) and Rat Spleen (lane 4), using TMAC-02822 diluted at 1:3,000. 3. IHC staining of mouse hippocampus tissue with NFκB p65 mouse mAb diluted at 1:200. ![]() ![]() ![]() |
| 应用 | IHCWB |
| 推荐剂量 | WB: 1:1000-3000; IHC: 1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Affinity purification using immunogen. |
| 性状 | Liquid |
| 缓冲液 | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | NFkB p65 is ubiquitinated leading to its proteosomal degradation, which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP, enhancing transcriptional activity. NFkB p65 is also acetylated at K122, enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB, which coordinates various aspects of immune function required for resistance to infection. |
| 偶联 | Unconjugated |
| Uniprot ID |
| 分子量 | Actual: 65 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |