Name: Anti-TMEFF2 Antibody
Brand: TargetMol
SKU: T9901A-1352
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-TMEFF2 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human TMEFF2 protein (Tomoregulin-1) with exceptional binding affinity. It effectively facilitates the measurable detection of TMEFF2-positive malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads like Auristatin E (MMAE) during strictly monitored laboratory observation periods and molecular investigations to evaluate the disruption of prostate cancer progression.
体外活性	在前列腺癌细胞系（LNCaP、C4-2B）中，Anti-TMEFF2 Antibody 偶联物诱导了细胞周期阻滞和凋亡，IC50 值处于低纳摩尔范围 [1]。
体内活性	在人前列腺癌异种移植模型（LuCaP 23.1、LuCaP 35）中，通过全身给药方式给予 Anti-TMEFF2 Antibody 偶联物显著抑制了肿瘤生长并导致肿瘤退缩 [1]。
别名	抗TMEFF2抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	Q9UIK5
靶点	TMEFF2

储存&溶解度

存储

Anti-TMEFF2 Antibody