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Anti-CTLA4 Antibody (3L241)
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还可以产品编号 TMAH-00311
别名 IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Anti-CTLA4 Antibody (3L241) 是一种抗体，靶向 CTLA4。Anti-CTLA4 Antibody (3L241) 可用于 ELISA,IHC。
Anti-CTLA4 Antibody (3L241)
Anti-CTLA4 Antibody (3L241)
一键复制产品信息 还可以产品编号 TMAH-00311 别名 IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5
Anti-CTLA4 Antibody (3L241) 是一种抗体，靶向 CTLA4。Anti-CTLA4 Antibody (3L241) 可用于 ELISA,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CTLA4 Antibody (3L241) is an antibody targeting CTLA4. Anti-CTLA4 Antibody (3L241) can be used in ELISA,IHC. |
| 别名 | IDDM12, ICOS, GSE, GRD4, CTLA4, CELIAC3, CD152, ALPS5 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3L241 |
| 交叉反应 | Human |
| 验证活性 | 1. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00311 diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISAIHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization. |
| 组织特异性 | Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human CTLA4 (CD152) |
| 抗原种属 | Human |
| 基因名称 | CTLA4 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology, Stem cells |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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