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Anti-BACE1 Antibody (2J206)

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货号 TMAH-00101

别名 β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2

Anti-BACE1 Antibody (2J206) 是一种抗体,靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA,WB。

Anti-BACE1 Antibody (2J206)

Anti-BACE1 Antibody (2J206)

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Rating icon 还可以
货号 TMAH-00101 别名 β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2

Anti-BACE1 Antibody (2J206) 是一种抗体,靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍


生物活性
产品描述
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA,WB.
别名β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2
Ig Type
Rabbit IgG
克隆号
2J206
反应种属
Human, Mouse, Rat
验证活性
Western Blot
-Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Mouse brain tissue
-All lanes: BACE1 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 56, 53, 52, 49, 46, 43 kDa
-Observed band size: 72 kDa
应用ELISAWB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane raft. Lysosome. Late endosome. Early endosome. Recycling endosome. Cell projection, axon. Cell projection, dendrite.
组织特异性Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human BACE1
抗原种属
Human
基因名称
BACE1
基因ID
Uniprot ID
研究领域
Neuroscience, Cell biology
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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