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Anti-BACE1 Antibody (2J206) 是一种抗体,靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA, WB。
Anti-BACE1 Antibody (2J206) 是一种抗体,靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA, WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,305 | 5日内发货 | |
100 μL | ¥ 2,195 | 5日内发货 |
产品描述 | Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB. |
别名 | β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2 |
Ig Type | Rabbit IgG |
克隆号 | 2J206 |
交叉反应 | Human, Mouse, Rat |
验证活性 | Western Blot -Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Mouse brain tissue -All lanes: BACE1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 56, 53, 52, 49, 46, 43 kDa -Observed band size: 72 kDa |
应用 | ELISA, WB |
推荐剂量 | WB:1:500-1:5000. |
抗体种类 | Monoclonal |
亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane raft. Lysosome. Late endosome. Early endosome. Recycling endosome. Cell projection, axon. Cell projection, dendrite. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human BACE1 |
抗原种属 | Human |
基因ID | 23621 |
Uniprot ID | |
研究领域 | Neuroscience, Cell biology |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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