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Anti-BACE1 Antibody (2J206)
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产品编号 TMAH-00101
别名 β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2
Anti-BACE1 Antibody (2J206) 是一种抗体，靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA, WB。
Anti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206)
还可以产品编号 TMAH-00101 别名 β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2
Anti-BACE1 Antibody (2J206) 是一种抗体，靶向 BACE1。Anti-BACE1 Antibody (2J206) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB. |
| 别名 | β-site APP-cleaving enzyme 1, HSPC104, beta-site APP-cleaving enzyme 1, BACE, ASP2 |
| Ig Type | Rabbit IgG |
| 克隆号 | 2J206 |
| 交叉反应 | Human, Mouse, Rat |
| 验证活性 | Western Blot -Positive WB detected in: MCF-7 whole cell lysate, Rat brain tissue, Mouse brain tissue -All lanes: BACE1 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 56, 53, 52, 49, 46, 43 kDa -Observed band size: 72 kDa |
| 应用 | |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Endoplasmic reticulum. Endosome. Cell surface. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Membrane raft. Lysosome. Late endosome. Early endosome. Recycling endosome. Cell projection, axon. Cell projection, dendrite. |
| 组织特异性 | Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human BACE1 |
| 抗原种属 | Human |
| 基因名称 | BACE1 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cell biology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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