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Anti-RARA Antibody (6U643) 是一种 Rabbit 抗体,靶向 RARA。Anti-RARA Antibody (6U643) 可用于 WB,FCM。
Anti-RARA Antibody (6U643) 是一种 Rabbit 抗体,靶向 RARA。Anti-RARA Antibody (6U643) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-RARA Antibody (6U643) is a Rabbit antibody targeting RARA. Anti-RARA Antibody (6U643) can be used in WB,FCM. |
别名 | Retinoic acid receptor alpha polypeptide, Retinoic acid receptor alpha, Retinoic acid nuclear receptor alpha variant 2, Retinoic acid nuclear receptor alpha variant 1, RARalpha1, RARalpha, RAR alpha, RAR, Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form, Nuclear receptor subfamily 1 group B member 1, Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein, NR1B1 |
Ig Type | IgG |
交叉反应 | Human,Mouse |
应用 | |
推荐剂量 | WB: 1:1000; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Retinoids (RA) are metabolites of vitamin A (retinol) that are important signaling molecules during vertebrate development and tissue differentiation. RAs activate the retinoic acid receptor (RAR) and retinoid X receptor (RXR) nuclear transcription factor families. Most retinoid forms activate RAR family members, whereas RXR family members are activated by 9-cis-RA only. RAR family members, which include RARα, RARβ and RARγ, have a high affinity for all transretinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. The human RARα gene maps to chromosome 17 and is implicated in the chromosomal translocation associated with acute promyelocytic leukemia (APL-M3). Specifically, the RARα gene is fused with the promyelocytic leukemia (PML) gene, which encodes the fusion protein PML/RARα. The PML/RARα fusion protein inhibits PML-dependent apoptotic pathways and halts myeloid differentiation at the promyelocytic stage. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 55 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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