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Anti-IL-20 Antibody (9U513) 是一种 Mouse 抗体,靶向 IL-20。Anti-IL-20 Antibody (9U513) 可用于 ELISA,ELISA(Det)。
Anti-IL-20 Antibody (9U513) 是一种 Mouse 抗体,靶向 IL-20。Anti-IL-20 Antibody (9U513) 可用于 ELISA,ELISA(Det)。
产品描述 | Anti-IL-20 Antibody (9U513) is a Mouse antibody targeting IL-20. Anti-IL-20 Antibody (9U513) can be used in ELISA,ELISA(Det). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 9U513 |
交叉反应 | Human |
应用 | ELISA,ELISA(Det) |
推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-20 (rh IL-20; TMPY-02959; Q9NYY1; Leu25-Glu176). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. It has been shown that interleukin-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL-20 Protein (TMPY-02959) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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