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Anti-CD58 Antibody-FITC (8M86) 是一种 FITC-conjugated Mouse 抗体,靶向 CD58。Anti-CD58 Antibody-FITC (8M86) 可用于 FCM。
Anti-CD58 Antibody-FITC (8M86) 是一种 FITC-conjugated Mouse 抗体,靶向 CD58。Anti-CD58 Antibody-FITC (8M86) 可用于 FCM。
产品描述 | Anti-CD58 Antibody-FITC (8M86) is a FITC-conjugated Mouse antibody targeting CD58. Anti-CD58 Antibody-FITC (8M86) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 8M86 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD58 expression on human whole blood lymphocytes. Cells were stained with conjugated anti-Human CD58. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LFA-3 / CD58 (rh LFA-3 / CD58; TMPY-03489; AAH05930.1; Met1-Arg215) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | FITC |
其他可选修饰符 | Unconjugated/PerCP/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human LFA-3 / CD58 Protein (TMPY-03489) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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