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顶部相关产品产品介绍化学信息储存和溶解信息计算器

Dimethyldioctadecylammonium (bromide)

货号 T36357Cas号 3700-67-2 一键复制产品信息
Rating icon 很棒

Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.

Dimethyldioctadecylammonium (bromide)

一键复制产品信息
Rating icon 很棒
货号 T36357Cas号 3700-67-2

Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.

Dimethyldioctadecylammonium (bromide)
规格价格库存数量
1 g
¥ 138
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5 g
¥ 283
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10 g
¥ 393
现货
25 g
¥ 638
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实验操作小课堂
常见问题解答
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颜色: 白色
性状: Solid
资源下载: COA MS HNMR产品操作手册

产品介绍

生物活性
产品描述
Dimethyldioctadecylammonium (DDA) is a cationic amphipathic lipid. DDA liposomes containing an Ag85B-ESAT-6 antigen induce antigen deposition at an intramuscular or subcutaneous injection site in mice, increasing immune cell exposure to the antigen. In a guinea pig model of M. tuberculosis infection, spleen bacterial load is reduced and lung and spleen lesion numbers are decreased when the mycobacterial lipid antigens Ac2SGL and PIM2 are administered in liposomes comprised of DDA and a synthetic analog of the mycobacterial cord factor trehalose 6,6-dibehenate (TDB). DDA has also been used in the study of lipid bilayer dynamics.
化学信息
分子量630.95
分子式C38H80BrN
CAS No.3700-67-2
Smiles[Br-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC
密度1.047 g/cm3
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

实际储存温度请以COA为准

溶解度信息
Ethanol: 33 mg/mL (52.3 mM), Sonication is recommended.
DMSO: 16 mg/mL (25.36 mM), Sonication is recommended.
DMF: 2 mg/mL (3.17 mM), Sonication is recommended.
PBS (pH 7.2): 5 mg/mL (7.92 mM), Sonication is recommended.
溶液配制表
DMF/PBS (pH 7.2)/DMSO/Ethanol
1mg5mg10mg50mg
1 mM1.5849 mL7.9246 mL15.8491 mL79.2456 mL
PBS (pH 7.2)/DMSO/Ethanol
1mg5mg10mg50mg
5 mM0.3170 mL1.5849 mL3.1698 mL15.8491 mL
DMSO/Ethanol
1mg5mg10mg50mg
10 mM0.1585 mL0.7925 mL1.5849 mL7.9246 mL
20 mM0.0792 mL0.3962 mL0.7925 mL3.9623 mL
Ethanol
1mg5mg10mg50mg
50 mM0.0317 mL0.1585 mL0.3170 mL1.5849 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

Dimethyldioctadecylammonium (bromide)Dimethyldioctadecylammonium
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