Name: CDNF Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-01916
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 336

6-8日内发货

10 μg

¥ 538

6-8日内发货

20 μg

¥ 858

5日内发货

50 μg

¥ 1,700

5日内发货

100 μg

¥ 3,380

5日内发货

200 μg

¥ 4,970

5日内发货

500 μg

¥ 10,600

5日内发货

1 mg

¥ 21,800

5日内发货

生物活性

产品描述	CDNF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is Q8CC36.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Cerebral Dopamine Neurotrophic Factor (CDNF), also known as ARMETL1 (ARMET-like protein 1), is a secreted protein with eight conserved cysteine residues, predicting a unique protein fold and defining a new, evolutionarily conserved protein family. CDNF is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons comparable to that of glial cell line-derived neurotrophic factor (GDNF). CDNF/ARMETL1 is a evolutionary conserved protein which can protect and restore the function of dopaminergic neurons in the rat model of Parkinson's disease, suggesting that CDNF might be beneficial for the treatment of Parkinson's disease. CDNF is widely expressed in neurons in several brain regions including cerebral cortex, hippocampus, substantia nigra, striatum and cerebellum. Human CDNF is glycosylated and secreted from transiently transfected cells. CDNF promotes the survival, growth, and function of dopamine-specific neurons and is expressed in brain regions that undergo cocaine-induced neuroplasticity.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q8CC36
蛋白构建	A DNA sequence encoding the mouse CDNF (NP_808315.1) (Met 1-Leu 187) was expressed, with a polyhistidine tag at the C-terminus. Predicted N terminal: Gln 25
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	cerebral dopamine neurotrophic factor, Armetl1, 9330140G23
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	20 kDa (predicted); 20 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

CDNF Protein, Mouse, Recombinant (His)

CDNF Protein, Mouse, Recombinant (His)

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