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Anti-NF-H Antibody (6E806)

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货号 TMAB-09428

Anti-NF-H Antibody (6E806) 是一种 Rabbit 抗体,靶向 NF-H。Anti-NF-H Antibody (6E806) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-NF-H Antibody (6E806)

Anti-NF-H Antibody (6E806)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09428

Anti-NF-H Antibody (6E806) 是一种 Rabbit 抗体,靶向 NF-H。Anti-NF-H Antibody (6E806) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-NF-H Antibody (6E806) is a Rabbit antibody targeting NF-H. Anti-NF-H Antibody (6E806) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6E806
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Neurofilaments can be defined as the intermediate or 10nm filaments found in specifically in neuronal cells. When visualised using an electron microscope, neurofilaments appear as 10nm diameter fibres of indeterminate length that generally have fine wispy protrusions from their sides. They are particularly abundant in axons of large projection neurons. They probably function to provide structural support for neurons and their synapses and to support the large axon diameters required for rapid conduction of impulses down axons. Neurofilaments are composed of a mixture of subunits, which usually includes the three neurofilament triplet proteins neurofilament light (NFL), neurofilament medium (NFM) and neurofilament heavy (NFH). Neurofilaments may also include smaller amounts of peripherin, alpha internexin, nestin and in some cases vimentin. Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons, and are biochemically very stable. Some studies have shown that levels of neurofilament heavy and neurofilament light are elevated in patients with Alzheimer's disease, frontotemporal lobe dementia, and vascular dementia.
抗原信息
免疫原
A synthesized peptide: human Neurofilament heavy polypeptide
抗原种属
Human
基因名称
NEFH
基因ID
蛋白名称
Neurofilament heavy polypeptide
Uniprot ID
功能
Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins.
化学信息
分子量Theoretical: 118 kDa. Actual: 200 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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