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Anti-Osteoactivin/GPNMB Antibody (7E107)
还可以产品编号 TMAY-01838
Anti-Osteoactivin/GPNMB Antibody (7E107) 是一种 Rabbit 抗体，靶向 Osteoactivin/GPNMB。Anti-Osteoactivin/GPNMB Antibody (7E107) 可用于 ELISA。
Anti-Osteoactivin/GPNMB Antibody (7E107)
Anti-Osteoactivin/GPNMB Antibody (7E107)
还可以产品编号 TMAY-01838
Anti-Osteoactivin/GPNMB Antibody (7E107) 是一种 Rabbit 抗体，靶向 Osteoactivin/GPNMB。Anti-Osteoactivin/GPNMB Antibody (7E107) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Osteoactivin/GPNMB Antibody (7E107) is a Rabbit antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (7E107) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7E107 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human GPNMB / Osteoactivin (rh GPNMB / Osteoactivin; TMPY-02143; Q14956-2; Met1-Pro474). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteoclasts, macrophages, dendritic cells, and tumor cells. It is suggested to influence osteoblast maturation, cell adhesion, and migration. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization and functions as a negative regulator of inflammation in macrophages. Osteoactivin is expressed at high levels in normal and inflammatory liver macrophages suggesting a significant role in acute liver injury. The early-phase upregulation of Osteoactivin expression in the tubular epithelium in response to renal injury might play a role in triggering renal interstitial fibrosis via activation of matrix metalloproteinase expression and collagen remodeling in rats. Osteoactivin is a protein that is expressed in aggressive human breast cancers and is capable of promoting breast cancer metastasis to bone. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human GPNMB / Osteoactivin Protein (TMPY-02143) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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