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Anti-CD59 Antibody-APC (6Z816)
还可以产品编号 TMAY-03805A
Anti-CD59 Antibody-APC (6Z816) 是一种 APC-conjugated Rabbit 抗体，靶向 CD59。Anti-CD59 Antibody-APC (6Z816) 可用于 FCM。
Anti-CD59 Antibody-APC (6Z816)
Anti-CD59 Antibody-APC (6Z816)
还可以产品编号 TMAY-03805A
Anti-CD59 Antibody-APC (6Z816) 是一种 APC-conjugated Rabbit 抗体，靶向 CD59。Anti-CD59 Antibody-APC (6Z816) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CD59 Antibody-APC (6Z816) is a APC-conjugated Rabbit antibody targeting CD59. Anti-CD59 Antibody-APC (6Z816) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 6Z816 |
| 交叉反应 | Rat |
| 验证活性 | Flow cytometric analysis of Rat CD59 expression on SD rat bone marrow cells. Cells were stained with APC-conjugated anti-Rat CD59. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD59 (rR CD59; TMPY-03091; P27274; Met1-Asn100) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Rat CD59 Protein (TMPY-03091) |
| 抗原种属 | Rat |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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