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Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-C-ABL1/2 (Tyr393/439)。Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-C-ABL1/2 (Tyr393/439)。Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody 可用于 WB,IHC,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody is a Rabbit antibody targeting Phospho-C-ABL1/2 (Tyr393/439). Anti-Phospho-C-ABL1/2 (Tyr393/439) Polyclonal Antibody can be used in WB,IHC,IF. |
别名 | p-C-ABL1/2 (Y393/439), p-C-ABL1/2 (Tyr393/439), C-ABL1/2 (p-Y393/439), C-ABL1/2 (p-Tyr393/439) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ABL1/2(Phospho-Tyr393/439) Antibody TMAC-00049(left) or the same antibody preincubated with blocking peptide(right). 2. Immunofluorescence staining of methanol-fixed Hela cells using ABL1/2(phospho-Tyr393/439) Antibody TMAC-00049. 3. Western blot analysis of extracts from HL60 cells using ABL1/2(phospho-Tyr393/439) Antibody TMAC-00049 and the same antibody preincubated with blocking peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-100; IF: 1:100-200 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 393/439 (D-T-Y(p)-T-A) derived from Human ABL1/2 |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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