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Anti-NUDT5 Antibody (4D504)
还可以产品编号 TMAH-00836
别名 YSAH1, YSA1H, YSA1, nudix (nucleoside diphosphate linked moiety X)-type motif 5, hYSAH1
Anti-NUDT5 Antibody (4D504) 是一种抗体，靶向 NUDT5。Anti-NUDT5 Antibody (4D504) 可用于 ELISA, WB, FC。
Anti-NUDT5 Antibody (4D504)
Anti-NUDT5 Antibody (4D504)
还可以产品编号 TMAH-00836 别名 YSAH1, YSA1H, YSA1, nudix (nucleoside diphosphate linked moiety X)-type motif 5, hYSAH1
Anti-NUDT5 Antibody (4D504) 是一种抗体，靶向 NUDT5。Anti-NUDT5 Antibody (4D504) 可用于 ELISA, WB, FC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-NUDT5 Antibody (4D504) is an antibody targeting NUDT5. Anti-NUDT5 Antibody (4D504) can be used in ELISA, WB, FC. |
| 别名 | YSAH1, YSA1H, YSA1, nudix (nucleoside diphosphate linked moiety X)-type motif 5, hYSAH1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4D504 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: Hela whole cell lysate -All lanes: NUDT5 antibody at 1:2000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 25 kDa -Observed band size: 36 kDa 2. Overlay Peak curve showing HepG2 cells stained with TMAH-00836 (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISA, WB, FC |
| 推荐剂量 | WB:1:500-1:2000; FC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate. In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity. In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human NUDT5 |
| 抗原种属 | Human |
| 基因ID | 11164 |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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