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Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody

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Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody
产品编号 TMAC-02959
别名 p-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182), MAPK14 (p-Tyr182)

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MAPK14 (Tyr182)。Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody
产品编号 TMAC-02959 别名 p-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182), MAPK14 (p-Tyr182)

Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MAPK14 (Tyr182)。Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAPK14 (Tyr182). Anti-Phospho-MAPK14 (Tyr182) Polyclonal Antibody can be used in WB,IHC.
别名p-MAPK14 (Y182), p-MAPK14 (Tyr182), MAPK14 (p-Y182), MAPK14 (p-Tyr182)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from Hela cells untreated or treated with UV for the indicated times, using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959 (left) or the same antibody preincubated with blocking peptide (right).
3. Western blot analysis of extracts from Hela cells, treated with TNFa or calf intestinal phosphatase (CIP), using P38 MAPK (Phospho-Tyr182) Antibody TMAC-02959.
应用
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 182 (T-G-Y(p)-V-A) derived from Human P38 MAPK
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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