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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PRDM16 Antibody (2M360)

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货号 TMAB-11718

Anti-PRDM16 Antibody (2M360) 是一种 Mouse 抗体，靶向 PRDM16。Anti-PRDM16 Antibody (2M360) 可用于 WB。

Anti-PRDM16 Antibody (2M360)

Anti-PRDM16 Antibody (2M360)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11718

Anti-PRDM16 Antibody (2M360) 是一种 Mouse 抗体，靶向 PRDM16。Anti-PRDM16 Antibody (2M360) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-PRDM16 Antibody (2M360) is a Mouse antibody targeting PRDM16. Anti-PRDM16 Antibody (2M360) can be used in WB.
Ig Type
IgG1, k
克隆号
2M360
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus.
组织特异性Expressed in uterus and kidney.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human PRDM16 between 779-996 amino acids
抗原种属
Human
基因名称
PRDM16
基因ID
63976
蛋白名称
Histone-lysine N-methyltransferase PRDM16
Uniprot ID
Q9HAZ2
功能
Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
化学信息
分子量Theoretical: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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