Name: LY341495
Brand: TargetMol
SKU: T15816
Price: 554 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

2 mg

¥ 554

现货

5 mg

¥ 913

现货

1 mL x 10 mM (in DMSO)

¥ 983

现货

生物活性

产品描述	LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used for the study of neurological disorders.
靶点活性	mGluR8:170 nM, mGluR1a:7.8 μM, mGluR7:990 nM, mGluR2:21 nM, mGluR5a:8.2 μM, mGluR3:21 μM, mGluR4:22 μM
体内活性	急性给药 LY341495 (3.0 mg/kg)可降低 pAkt 和 pGSK-3 水平，但需要反复给药(3.0 mg/kg)才能降低 b-连环蛋白水平[2]。

化学信息

分子量	353.37
分子式	C₂₀H₁₉NO₅
CAS No.	201943-63-7
Smiles	N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O
密度	1.432 g/cm3

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 5 mg/mL (14.15 mM), Sonication is recommended.

H2O: < 0.1 mg/mL (insoluble)

溶液配制表

DMSO

LY341495