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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-OGG1 Polyclonal Antibody

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货号 TMAB-09756

Anti-OGG1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OGG1。Anti-OGG1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-OGG1 Polyclonal Antibody

Anti-OGG1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09756

Anti-OGG1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 OGG1。Anti-OGG1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-OGG1 Polyclonal Antibody is a Rabbit antibody targeting OGG1. Anti-OGG1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion; Nucleus and Nucleus > nucleoplasm. Nucleus speckle. Nucleus matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human OGG1/8 hydroxyguanine DNA glycosylase
抗原种属
Human
基因名称
OGG1
基因ID
4968
蛋白名称
N-glycosylase/DNA lyase
Uniprot ID
O15527
功能
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
化学信息
分子量Theoretical: 38-47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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