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Anti-C1D Antibody (6U107) 是一种 Rabbit 抗体,靶向 C1D。Anti-C1D Antibody (6U107) 可用于 WB。
Anti-C1D Antibody (6U107) 是一种 Rabbit 抗体,靶向 C1D。Anti-C1D Antibody (6U107) 可用于 WB。
产品描述 | Anti-C1D Antibody (6U107) is a Rabbit antibody targeting C1D. Anti-C1D Antibody (6U107) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6U107 |
交叉反应 | Human |
验证活性 | Anti-C1D rabbit monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:16 kDa. -Observed band size:16 kDa |
应用 | WB |
推荐剂量 | WB: 1:500-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human C1D (rh C1D; TMPY-02883; Q13901; Met1-Ser141). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressorcan activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner. |
偶联 | Unconjugated |
免疫原 | Recombinant Human C1D protein (TMPY-02883) |
抗原种属 | Human |
研究领域 | Apoptosis Transcription Factors and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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