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AMG-811是一种由CHO细胞表达的全人源单克隆抗体,特异性靶向干扰素γ(IFN-γ),通过中和其与受体的结合抑制下游炎症信号通路。AMG-811常用于研究IFN-γ介导的免疫反应及其在自身免疫疾病(如系统性红斑狼疮)中的作用。
AMG-811是一种由CHO细胞表达的全人源单克隆抗体,特异性靶向干扰素γ(IFN-γ),通过中和其与受体的结合抑制下游炎症信号通路。AMG-811常用于研究IFN-γ介导的免疫反应及其在自身免疫疾病(如系统性红斑狼疮)中的作用。


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| 产品描述 | AMG-811 is a fully humanized monoclonal antibody expressed by CHO cells, which specifically targets interferon-γ (IFN-γ) and inhibits the downstream inflammatory signaling pathway by neutralizing its binding to the receptor. AMG-811 is often used to study the immune response mediated by IFN-γ and its role in autoimmune diseases (such as systemic lupus erythematosus). |
| 反应种属 | Human |
| 应用 | ELISAFACSFunctional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | IFNg |
| CAS No. | 1439393-01-7 |
| 存储 | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
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