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Anti-APPL1 Antibody (2A728)

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货号 TMAB-02786

Anti-APPL1 Antibody (2A728) 是一种 Rabbit 抗体,靶向 APPL1。Anti-APPL1 Antibody (2A728) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-APPL1 Antibody (2A728)

Anti-APPL1 Antibody (2A728)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02786

Anti-APPL1 Antibody (2A728) 是一种 Rabbit 抗体,靶向 APPL1。Anti-APPL1 Antibody (2A728) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-APPL1 Antibody (2A728) is a Rabbit antibody targeting APPL1. Anti-APPL1 Antibody (2A728) can be used in WB,IHC-P,IHC-Fr,IF.
克隆号
2A728
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Early endosome membrane; Peripheral membrane protein. Nucleus. Note=Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF.
组织特异性High levels in heart, ovary, pancreas and skeletal muscle.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
A synthesized peptide: human Dip13 alpha
基因名称
APPL1
基因ID
蛋白名称
DCC-interacting protein 13-alpha
功能
Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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