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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HACE1 Polyclonal Antibody

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货号 TMAB-06872

Anti-HACE1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HACE1。Anti-HACE1 Polyclonal Antibody 可用于 FCM。

Anti-HACE1 Polyclonal Antibody

Anti-HACE1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06872

Anti-HACE1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HACE1。Anti-HACE1 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HACE1 Polyclonal Antibody is a Rabbit antibody targeting HACE1. Anti-HACE1 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse)
应用FCM
推荐剂量
FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Endoplasmic reticulum. A significant portion localizes to the endoplasmic reticulum.
组织特异性Expressed in multiple tissues including heart, brain and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HACE1
抗原种属
Human
基因名称
HACE1
基因ID
57531
蛋白名称
E3 ubiquitin-protein ligase HACE1
Uniprot ID
Q8IYU2
功能
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
化学信息
分子量Theoretical: 90-102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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