购物车
- 全部删除
- 您的购物车当前为空
Anti-ATG12 Antibody (2H769) 是一种抗体,靶向 ATG12。Anti-ATG12 Antibody (2H769) 可用于 ELISA。
Anti-ATG12 Antibody (2H769) 是一种抗体,靶向 ATG12。Anti-ATG12 Antibody (2H769) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,315 | 5日内发货 | |
100 μL | ¥ 2,190 | 5日内发货 |
产品描述 | Anti-ATG12 Antibody (2H769) is an antibody targeting ATG12. Anti-ATG12 Antibody (2H769) can be used in ELISA. |
别名 | Ubiquitin-like protein ATG12, HAPG12, FBR93, Autophagy-related protein 12, Autophagy 12, ATG12 autophagy related 12 homolog (S. cerevisiae), ATG12 autophagy related 12 homolog, ATG 12, APG12-like, APG12L |
Ig Type | Rabbit IgG |
克隆号 | 2H769 |
交叉反应 | Human |
应用 | ELISA |
抗体种类 | Monoclonal |
亚细胞定位 | Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane. |
构建方式 | Recombinant Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. (Microbial infection) May act as a proviral factor. In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection. Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for the initiation of HCV replication, but not required once infection is established. |
偶联 | Unconjugated |
免疫原 | A synthetic peptide: Human ATG12 |
抗原种属 | Human |
基因ID | 9140 |
Uniprot ID | |
研究领域 | Cell Biology |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容