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Anti-B7-1 Antibody-Biotin (4I630)

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产品编号 TMAY-01080B

别名 CD80 molecule

Anti-B7-1 Antibody-Biotin (4I630) 是一种 Biotin-conjugated Mouse 抗体，靶向 B7-1。Anti-B7-1 Antibody-Biotin (4I630) 可用于 ELISA。

Anti-B7-1 Antibody-Biotin (4I630)

Anti-B7-1 Antibody-Biotin (4I630)

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产品编号 TMAY-01080B 别名 CD80 molecule

Anti-B7-1 Antibody-Biotin (4I630) 是一种 Biotin-conjugated Mouse 抗体，靶向 B7-1。Anti-B7-1 Antibody-Biotin (4I630) 可用于 ELISA。

规格价格库存数量
20 μg
¥ 785
5日内发货
100 μg
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-B7-1 Antibody-Biotin (4I630) is a Biotin-conjugated Mouse antibody targeting B7-1. Anti-B7-1 Antibody-Biotin (4I630) can be used in ELISA.
别名CD80 molecule
Ig Type
Mouse IgG1
克隆号
4I630
交叉反应
Human
特异性
Human B7-1/CD80
应用ELISA
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD80 / B7-1 (rh CD80 / B7-1; TMPY-01063; Met 1-Asn 242; NP_005182.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The B-lymphocyte activation antigen B7-1 (referred to as B7), also known as CD80, is a member of cell surface immunoglobulin superfamily and is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. As costimulatory ligands, B7-1 which exists predominantly as dimer and the related protein B7-2, interact with the costimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus constitute one of the dominant pathways that regulate T cell activation and tolerance, cytokine production, and the generation of CTL. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Biotin
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human CD80 / B7-1 Protein (TMPY-01063)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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