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TWEAKR/TNFRSF12A Protein, Human, Recombinant (aa 28-80, hFc) is expressed in HEK293 Cells. The accession number is Q9NP84-1.

| 规格 | 价格 | 库存 | 数量 | 
|---|
| 生物活性 | Immobilized Human TNFRSF12A, hFc Tag at 0.5 μg/ml (100 μl/Well) on the plate. Dose response curve for Biotinylated Anti-TNFRSF12A Antibody, hFc Tag with the EC50 of 13.8 ng/ml determined by ELISA (QC Test). Human TNFSF12, hFc Tag immobilized on CM5 Chip can bind Human TNFRSF12A, hFc Tag with an affinity constant of 0.24 nM as determined in SPR assay (Biacore T200). | 
| 产品描述 | TWEAKR/TNFRSF12A Protein, Human, Recombinant (aa 28-80, hFc) is expressed in HEK293 Cells. The accession number is Q9NP84-1. | 
| 种属 | Human | 
| 表达系统 | HEK293 Cells | 
| 标签 | N-hFc | 
| 蛋白编号 | Q9NP84-1 | 
| 别名 | TWEAKR,tumor necrosis factor receptor superfamily member 12A,FN14,CD266 | 
| 蛋白构建 | Glu28-Per80 | 
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE | 
| 分子量 | 32.9 kDa (Predicted); 38-45 kDa (Due to glycosylation) | 
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. | 
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| 研究背景 | Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck.TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer, in addition, PPAR signaling pathway, insulin signaling pathway, mTOR signaling pathway may be the key pathway controlled by TNFRSF12A in thyroid cancer. Further experimental ought to be performed to demonstrate the biologic effect of TNFRSF12A. |