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Anti-Siglec-2/CD22 Antibody (3K71)

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Anti-Siglec-2/CD22 Antibody (3K71)
产品编号 TMAH-00182
别名 SIGLEC-2, SIGLEC2, CD22 molecule

Anti-Siglec-2/CD22 Antibody (3K71) 是一种抗体，靶向 Siglec-2/CD22。Anti-Siglec-2/CD22 Antibody (3K71) 可用于 ELISA, IHC。

Anti-Siglec-2/CD22 Antibody (3K71)

Anti-Siglec-2/CD22 Antibody (3K71)

Rating icon 还可以
Anti-Siglec-2/CD22 Antibody (3K71)
产品编号 TMAH-00182 别名 SIGLEC-2, SIGLEC2, CD22 molecule

Anti-Siglec-2/CD22 Antibody (3K71) 是一种抗体，靶向 Siglec-2/CD22。Anti-Siglec-2/CD22 Antibody (3K71) 可用于 ELISA, IHC。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-Siglec-2/CD22 Antibody (3K71) is an antibody targeting Siglec-2/CD22. Anti-Siglec-2/CD22 Antibody (3K71) can be used in ELISA, IHC.
别名SIGLEC-2, SIGLEC2, CD22 molecule
Ig Type
Rabbit IgG
克隆号
3K71
交叉反应
Human
验证活性
IHC image of TMAH-00182 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用
ELISA, IHC
推荐剂量
IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Cell membrane; Single-pass type I membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human CD22
抗原种属
Human
基因ID
933
Uniprot ID
研究领域
Cancer, Immunology, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

SIGLEC 2

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