规格

价格

库存

数量

1 mg

¥ 395

现货

5 mg

¥ 947

现货

10 mg

¥ 1,410

现货

25 mg

¥ 3,090

现货

50 mg

¥ 4,530

现货

100 mg

¥ 6,480

现货

1 mL x 10 mM (in DMSO)

¥ 912

现货

生物活性

产品描述	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8.
体外活性	Boc-Asp(OME)-Fluoromethyl Keton（100μM；30分钟；多形核白细胞）可防止Fas诱导和自发性凋亡（-CH-11）[1]。在J774.1/JA-4细胞中，Boc-Asp(OME)-Fluoromethyl Keton（20μM；5小时）显著增加LDH释放[2]。
别名	Boc-Asp(OMe)-FMK, Boc-Asp(OMe)-fluoromethyl ketone

化学信息

分子量	263.26
分子式	C₁₁H₁₈FNO₅
CAS No.	187389-53-3
Smiles	[C@H](NC(OC(C)(C)C)=O)(CC(OC)=O)C(CF)=O
密度	1.150 g/cm3 at 20℃
颜色	Yellow
物理性状	Solid
Sequence	Boc-Asp(OMe)-CH2F

储存&溶解度

存储

keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (227.91 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7985 mL	18.9926 mL	37.9853 mL	189.9263 mL
5 mM	0.7597 mL	3.7985 mL	7.5971 mL	37.9853 mL
10 mM	0.3799 mL	1.8993 mL	3.7985 mL	18.9926 mL
20 mM	0.1899 mL	0.9496 mL	1.8993 mL	9.4963 mL
50 mM	0.0760 mL	0.3799 mL	0.7597 mL	3.7985 mL
100 mM	0.0380 mL	0.1899 mL	0.3799 mL	1.8993 mL