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Anti-c-Myc Polyclonal Antibody
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产品编号 TMAB-00451
别名 bHLHe39
Anti-c-Myc Polyclonal Antibody 是一种 Rabbit 抗体，靶向 c-Myc。Anti-c-Myc Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-c-Myc Polyclonal Antibody
Anti-c-Myc Polyclonal Antibody
还可以产品编号 TMAB-00451 别名 bHLHe39
Anti-c-Myc Polyclonal Antibody 是一种 Rabbit 抗体，靶向 c-Myc。Anti-c-Myc Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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产品介绍
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抗原信息
化学信息
| 产品描述 | Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| 别名 | bHLHe39 |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Dog,Pig,Cow,Rabbit,Sheep) |
| 验证活性 | Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-C-Myc Polyclonal Antibody, Unconjugated (TMAB-00451) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining |
| 应用 | |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus, nucleoplasm. |
| 组织特异性 | Low levels detected throughout embryo before cellular blastoderm formation, particularly concentrated in pole plasm. Zygotic expression detected during cellular blastoderm stage in endodermal anlagen of anterior and posterior midgut at both poles. After g |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human C-Myc |
| 抗原种属 | Human |
| 基因名称 | MYC |
| 基因ID | |
| 蛋白名称 | Myc proto-oncogene protein |
| Uniprot ID | |
| 研究领域 | Cell differentiation,Transcription factors,Oncoproteins,HLH / Leucine Zipper,Transcription Factors,c-myc,Nuclear |
| 功能 | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. |
| 分子量 | Theoretical: 49 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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