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Anti-HER4/ERBB4 Antibody (2P920)
还可以产品编号 TMAY-03534
Anti-HER4/ERBB4 Antibody (2P920) 是一种 Rabbit 抗体，靶向 HER4/ERBB4。Anti-HER4/ERBB4 Antibody (2P920) 可用于 ELISA。
Anti-HER4/ERBB4 Antibody (2P920)
Anti-HER4/ERBB4 Antibody (2P920)
还可以产品编号 TMAY-03534
Anti-HER4/ERBB4 Antibody (2P920) 是一种 Rabbit 抗体，靶向 HER4/ERBB4。Anti-HER4/ERBB4 Antibody (2P920) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-HER4/ERBB4 Antibody (2P920) is a Rabbit antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (2P920) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2P920 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ErbB4 / HER4 (rM ErbB4 / HER4; TMPY-03021; Q99P91; Met1-Leu652). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. And lower levels in thymus, lung, salivary gland, and pancreas. It specifically binds to and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. ERBB4 also can be activated by other factors and induces a variety of cellular responses including mitogenesis and differentiation. ERBB4 regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. It is required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. ERBB4 also play a role on the normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. It is required for mammary gland differentiation, induction of milk proteins and lactation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse ErbB4 / HER4 Protein (TMPY-03021) |
| 抗原种属 | Mouse |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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