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顶部生物活性储存和溶解信息计算器

Anti-HER4/ERBB4 Antibody (2P920)

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Anti-HER4/ERBB4 Antibody (2P920)
产品编号 TMAY-03534
别名 p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD

Anti-HER4/ERBB4 Antibody (2P920) 是一种 Rabbit 抗体，靶向 HER4/ERBB4。Anti-HER4/ERBB4 Antibody (2P920) 可用于 ELISA。

Anti-HER4/ERBB4 Antibody (2P920)
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Anti-HER4/ERBB4 Antibody (2P920)

Rating icon 还可以
Anti-HER4/ERBB4 Antibody (2P920)
产品编号 TMAY-03534 别名 p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD

Anti-HER4/ERBB4 Antibody (2P920) 是一种 Rabbit 抗体，靶向 HER4/ERBB4。Anti-HER4/ERBB4 Antibody (2P920) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-HER4/ERBB4 Antibody (2P920) is a Rabbit antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (2P920) can be used in ELISA.
别名p180erbB4, MGC138404, HER4, ErbB4, E4ICD, ALS19, 4ICD
Ig Type
Rabbit IgG
克隆号
2P920
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ErbB4 / HER4 (rM ErbB4 / HER4; TMPY-03021; Q99P91; Met1-Leu652).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景ERBB4 is a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. ERBB4 is expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. And lower levels in thymus, lung, salivary gland, and pancreas. It specifically binds to and is activated by neuregulins, NRG-2, NRG-3, heparin-binding EGF-like growth factor, betacellulin and NTAK. ERBB4 also can be activated by other factors and induces a variety of cellular responses including mitogenesis and differentiation. ERBB4 regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. It is required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. ERBB4 also play a role on the normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. It is required for mammary gland differentiation, induction of milk proteins and lactation.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse ErbB4 / HER4 Protein (TMPY-03021)
抗原种属
Mouse
研究领域
Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs)
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

MGC-138404MGC 138404HER-4HER 4ALS-19ALS 19

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4个月前
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