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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-NUMB Antibody (1M861)

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货号 TMAC-02905

别名 S171, Protein S171, Protein numb homolog, NUMB_HUMAN, Numb protein homolog, Numb homolog (Drosophila), Numb homolog, Numb, h-Numb, h Numb, FLJ31314, C14orf41, c14_5527

Anti-NUMB Antibody (1M861) 是一种 Rabbit 抗体，靶向 NUMB。Anti-NUMB Antibody (1M861) 可用于 ICC,IHC,WB。

Anti-NUMB Antibody (1M861)

Anti-NUMB Antibody (1M861)

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货号 TMAC-02905 别名 S171, Protein S171, Protein numb homolog, NUMB_HUMAN, Numb protein homolog, Numb homolog (Drosophila), Numb homolog, Numb, h-Numb, h Numb, FLJ31314, C14orf41, c14_5527

Anti-NUMB Antibody (1M861) 是一种 Rabbit 抗体，靶向 NUMB。Anti-NUMB Antibody (1M861) 可用于 ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-NUMB Antibody (1M861) is a Rabbit antibody targeting NUMB. Anti-NUMB Antibody (1M861) can be used in ICC,IHC,WB.
别名S171, Protein S171, Protein numb homolog, NUMB_HUMAN, Numb protein homolog, Numb homolog (Drosophila), Numb homolog, Numb, h-Numb, h Numb, FLJ31314, C14orf41, c14_5527
Ig Type
IgG
克隆号
1M861
反应种属
Human,Mouse,Rat
验证活性
1. Western blot analysis of NUMB on A431 cells lysates using anti-NUMB antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-NUMB antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded rat adrenal gland tissue using anti-NUMB antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-NUMB antibody. Counter stained with hematoxylin.
5. ICC staining NUMB in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining NUMB in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining NUMB in NIH/3T3 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICCIHCWB
推荐剂量
WB: 1:1000-5000; IHC: 1:50-100; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Neuronal cell fate decisions are directed in Drosophila by NUMB, a signaling adapter protein with two protein-protein interaction domains: a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). Mammalian NUMB homologs play a role in the determination of cell fates during development and bind with EPS15, LNX1, and NOTCH1. Conditional mouse mutants with deletion of NUMB in developing sensory ganglia show a reduction in axonal arborization in afferent fibers. Changes in cellular calcium homeostasis influences NUMB-dependent cell fate decisions during development of the nervous system. Chicken NUMB (c-NUMB) protein is localized to the basal cortex of mitotic neuroepithelial cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P49757
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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