Ibuprofen Piconol

Name: Ibuprofen Piconol
Brand: TargetMol
SKU: T7363
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.21%

货号 T7363Cas号 64622-45-3

别名 匹美诺芬, 布洛芬吡啶甲醇, U75630

Ibuprofen Piconol (U75630) 是非甾体抗炎药物，局部使用可缓解原发性热灼伤和晒伤。

Ibuprofen Piconol

一键复制产品信息

很棒

纯度: 99.21%

货号 T7363 别名 匹美诺芬, 布洛芬吡啶甲醇, U75630Cas号 64622-45-3

Ibuprofen Piconol (U75630) 是非甾体抗炎药物，局部使用可缓解原发性热灼伤和晒伤。

规格	价格	库存
50 mg	¥ 121	现货
100 mg	¥ 195	现货
200 mg	¥ 273	现货
1 mL x 10 mM (in DMSO)	¥ 99	现货

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纯度: 99.21%

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COA HNMR LCMS 产品操作手册

产品介绍

Ibuprofen Piconol AI Summary

Ibuprofen Piconol shows bioactivity in assays for identifying compounds that block entry of the Ebola virus, with AC50 values ranging from 707.9 nM to 14.13 µM, indicating potential efficacy in inhibiting viral entry. It also exhibits antiviral activity against SARS-CoV-2, with an inhibition index of 0.2174 in Vero E6 cells, which is lower than the control, and a hit score of 0.1126 in HRCE cells at MOI 0.4 after 96 hours, which is below the threshold for a confirmed hit. Additionally, Ibuprofen Piconol demonstrates moderate binding affinity towards human SLC6A2 (AC50 of 22103.4 nM), agonistic activity on human ADORA3 (AC50 of 15807.7 nM), binding affinity towards human PGR (AC50 of 19070.4 nM), and it inhibits human PTGS1 (AC50 of 10821.3 nM). For other tested assays, Ibuprofen Piconol did not exhibit significant activity or had AC50 values > 30000.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.
别名	匹美诺芬, 布洛芬吡啶甲醇, U75630

化学信息

分子量	297.39
分子式	C₁₉H₂₃NO₂
CAS No.	64622-45-3
Smiles	CC(C)Cc1ccc(cc1)C(C)C(=O)OCc1ccccn1
密度	1.0971 g/cm3 (Estimated)

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 50 mg/mL (168.13 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.73 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3626 mL	16.8129 mL	33.6259 mL	168.1294 mL
5 mM	0.6725 mL	3.3626 mL	6.7252 mL	33.6259 mL
10 mM	0.3363 mL	1.6813 mL	3.3626 mL	16.8129 mL
20 mM	0.1681 mL	0.8406 mL	1.6813 mL	8.4065 mL
50 mM	0.0673 mL	0.3363 mL	0.6725 mL	3.3626 mL
100 mM	0.0336 mL	0.1681 mL	0.3363 mL	1.6813 mL