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顶部产品介绍抗原信息储存和溶解信息计算器

Anti-COPS3 Antibody (5G111)

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货号 TMAB-04574

Anti-COPS3 Antibody (5G111) 是一种 Rabbit 抗体，靶向 COPS3。Anti-COPS3 Antibody (5G111) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-COPS3 Antibody (5G111)

Anti-COPS3 Antibody (5G111)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04574

Anti-COPS3 Antibody (5G111) 是一种 Rabbit 抗体，靶向 COPS3。Anti-COPS3 Antibody (5G111) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-COPS3 Antibody (5G111) is a Rabbit antibody targeting COPS3. Anti-COPS3 Antibody (5G111) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG/Kappa
克隆号
5G111
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic and Nuclear.
组织特异性Widely expressed. Expressed at high level in heart and skeletal muscle.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].
抗原信息
基因名称
COPS3
基因ID
8533
蛋白名称
COP9 signalosome complex subunit 3
功能
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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